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The Episode 1.46: The Secrets Behind the Ancient Love Poetry



Conclusion: Emergence agitation following general anesthesia is a common complication in adult nasal surgery patients. To reduce the occurrence and consequences of agitation episodes, elimination of the associated risk factors is necessary, especially in at-risk patients.




The Episode 1.46




Measurements of the aerosol hygroscopic growth factor, f(RH), and the physical and optical properties of aerosols were made at Gosan, Korea during the aerosol characterization experiment (ACE)-Asia 2001 field campaign (April 2001). The optical and hygroscopic properties of aerosols were characterized in terms of the air mass transport pathways. During the Asian dust period, σsp and σap were remarkably elevated with mean and standard deviation of 238.655.3 Mm -1 and 24.210.9 Mm -1, respectively. The mean f(RH) for the pollution aerosols from Chinese sectors (2.750.38) in this study was much higher than that for the anthropogenic aerosols in Europe during ACE-2 (1.460.10) as well as that of the urban/industrial aerosols of the US east coast during TARFOX (1.810.37-2.300.24). The mean f(RH) during the smoke period (1.600.20) was comparable to that during INDOEX (1.580.21), and higher than that for SCAR-B in Brazil (1.16). We found a negative correlation ( r=0.81) between f(RH) and OC concentration. This negative correlation suggests that organic aerosols have a strong influence on the smoke aerosol hygroscopicity.


Risk score=(former smoker1.47)+(current smoker2.48)+(unknown smoking status1.05)+(asthma0.64)+(1 episode of LRTI0.59)+(>1 episode of LRTI0.80)+(1 episode of cough0.35)+(>1 episode of cough0.57)+(1 episode of dyspnoea1.16)+(>1 episode of dyspnoea1.15)+(wheeze0.62)+(sputum0.40)+(unintended weight loss0.56)+(1 antibiotic course0.29)+(2 antibiotic course0.43)+(>2 antibiotic courses0.59)+(salbutamol1.43)+(prednisolone0.42).


PURPOSE: There is a debate about the effectiveness and toxicity of pelvic lymph node (PLN) irradiation for the treatment of men with high-risk prostate cancer. This study compared the toxicity of intensity-modulated radiation therapy (IMRT) to the prostate and the pelvic lymph nodes (PPLN-IMRT) with prostate-only IMRT (PO-IMRT). MATERIALS AND METHODS: Patients with high-risk localized or locally advanced prostate cancer treated with IMRT in the English National Health Service between 2010 and 2013 were identified by using data from the Cancer Registry, the National Radiotherapy Dataset, and Hospital Episode Statistics, an administrative database of all hospital admissions. Follow-up was available up to December 31, 2015. Validated indicators were used to identify patients with severe toxicity according to the presence of both a procedure code and diagnostic code in patient Hospital Episode Statistics records. A competing risks regression analysis, with adjustment for patient and tumor characteristics, estimated subdistribution hazard ratios (sHRs) by comparing GI and genitourinary (GU) complications for PPLN-IMRT versus PO-IMRT. RESULTS: Three-year cumulative incidence in the PPLN-IMRT (n = 780) and PO-IMRT (n = 3,065) groups was 14% for both groups for GI toxicity, and 9% and 8% for GU toxicity, respectively. Patients receiving PPLN-IMRT and PO-IMRT had similar levels of severe GI (adjusted sHR, 1.00; 95% CI, 0.80 to 1.24; P = .97) and GU (adjusted sHR, 1.10; 95% CI, 0.83 to 1.46; P = .50) toxicity rates. CONCLUSION: Including PLNs in radiation fields for high-risk or locally advanced prostate cancer is not associated with increased GI or GU toxicity at 3 years. Additional follow-up is required to answer questions about its impact on late GU toxicity. Results from ongoing trials will provide insight into the anticancer effectiveness of PLN irradiation.


Results: A total of 3520 participants from 15 RCTs were included. VESW regimen increased the incidence of acute rejection (AR) over controls (RR = 1.46, CI = 1.20-1.79, p = 0.04). Subsequent analysis demonstrated that such difference lost significance in patients receiving tacrolimus (p = 0.16), but remained significant in patients with cyclosporin (p 2ff7e9595c


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